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Here's Why Resveratrol is Natures Most Amazing "Cure All" Remedy!
March 24, 2018
Resveratrol – Why You Need it and How it Helps Extend Your Life…
Greetings everyone, and a warm welcome to our March edition of Life Saving Health Solutions - and an extra special welcome to all of our new subscribers. Thank you for being a part of our health circle and I sincerely hope you enjoy the information I’ll be sharing with you today.
Resveratrol and Living Longer…Recent research has found resveratrol may trigger a genetic expression that assists in extending human life span. This is the similar “life extension effect” associated with calorie restricted diets. Restricting calorie intake in laboratory animals has been shown to prolong their life span by as much as 60%. The same effect has not been overwhelmingly proven in humans yet, but the research is ongoing and looks very promising. Restricted calorie diets, however, do lack popularity for obvious reasons. No one likes starving themselves. The possibility that resveratrol may provide a similar benefit though has produced great interest.
Recent organism studies show resveratrol activates the molecular pathways that are involved in life-span extension. This effect has been demonstrated in yeast, worms, flies, fish, and mice. While this outcome hasn’t been demonstrated in humans, studies are continuing and initial results are encouraging. Research with mice found that resveratrol is able to reduce the harmful effects of high calorie diets, including metabolic changes caused by diabetes, liver and heart damage, and can even delay the onset of premature death from these conditions. Resveratrol enhances ones health and supports longevity via multiple means, including potent antioxidant effects/free radical scavenging, significant boosting of cellular energy production, and the influence of gene expression patterns similar to caloric restriction.
Resveratrol and Heart Health…Resveratrol and other polyphenols in wine are believed to be responsible for the so-called French Paradox. The French Paradox, the fact that the rate of coronary heart disease mortality in France is much lower than what it is in other industrialized countries, has been attributed to the high amount of red wine consumed by the French. While I’m not a big fan of regular alcohol consumption, I do believe that if you’re going to indulge in this practice, red wine is definitely your best option. The only down side is the high amount of harmful preservatives contained in most bottled red wines (you can get preservative free red wine though).
Resveratrol works by inhibiting the oxidation of low-density lipoprotein (LDL) cholesterol. It also inhibits smooth muscle cell proliferation and prevents platelet aggregation (blood platelets becoming sticky). In addition to this, resveratrol reduces the synthesis of lipids in the liver and inhibits the production of proatherogenic eicosanoids by human platelets and neutrophils. So basically, it helps maintain healthy levels of blood lipids and cholesterol, along with preventing the formation of arterial plaque (thereby reducing/preventing the hardening and thickening of arterial walls).
It’s believed that many of the beneficial effects of resveratrol are the result of its powerful antioxidant properties. These include the inhibition of LDL cholesterol oxidation and the increase in nitric oxide synthesis. Nitric oxide is crucial for vasodilation (dilation of blood vessels) and proper circulation.
Resveratrol – A Powerful Antioxidant…Resveratrol has been found to exert a strong inhibitory effect on superoxide anions (damaging pro-oxidants) and hydrogen peroxide production. It’s also been found to decrease pro-inflammatory arachidonic acid release and has potent hydroxyl-radical scavenging activity and glutathione-sparing activity. These benefits make resveratrol one of the most, if not THE MOST powerful antioxidants discovered thus far.
Cancer and Resveratrol…Resveratrol is being actively researched as both a cancer preventive and cancer treatment. Resveratrol is a broad-spectrum agent that stops cancer in lots of different ways, including blocking estrogen and androgen hormones, along with modulating genes. Recent research shows that resveratrol kills cancer cells regardless of whether they do or don’t have the tumor suppressor gene. It also works regardless of whether cancer cells are estrogen receptor-positive or negative. Cancer types that are known to be responsive to resveratrol include colon, neuroblastoma, esophageal, breast (all types), prostate (all types), leukemia, bone, skin, pancreas, ovarian, melanoma, liver, lung, stomach, oral, cervical, lymphoma and thyroid cancer.
In addition to its direct anti-cancer properties, resveratrol also acts as a synergist for other cancer treatments. For example, vitamin D3 converts to a steroid that inhibits the growth of breast cancer cells, and researchers have found that resveratrol significantly increases the effect of vitamin D. Other research shows that resveratrol causes drug-resistant non-Hodgkin's lymphoma cancer cells to become susceptible to chemotherapy drugs. Further research shows that resveratrol inhibits the ability of cancer cells to metastasize (spread), particularly to the bones.
The typical Western diet contains a disproportionate amount of linoleic acid. Our bodies convert a small amount of dietary linoleic acid to arachidonic acid, which is then converted to hormone-like substances that promote inflammatory processes known to stimulate cancer cell growth. In a study from Japan, resveratrol inhibited the growth of breast cancer cells and blocked the cancer growth-promoting effects of linoleic acid and arachidonic acid.
Alzheimer's and Resveratrol…Alzheimer's patients produce an abnormal protein known as beta-amyloid in their brains. Beta-amyloid causes increased levels of free radicals and oxidative stress, which in turn damages and kills brain cells. It’s been discovered that resveratrol protects the brain against oxidative stress and keeps brain cells alive and healthy. Research shows that adding additional antioxidants to resveratrol provides an even greater degree of protection than from just using the resveratrol on its own. Additional antioxidants include vitamins C and E.
Researchers have also discovered that resveratrol actually promotes the clearance/removal of any amyloid-beta molecules that may have already formed in the brain. It apparently destroys these amyloid-beta’s by producing intracellular proteasomes that attack and dissolve the amyloid-beta plaque. Researchers have also found that resveratrol activates a gene that prolongs lifespan and that this same gene protects the brain from damage caused by amyloid-beta plaque. What this means is not only can resveratrol protect the brain from dementia related diseases such as Alzheimer’s, it may even be able to reverse these conditions.
Resveratrol and Herpes Family Viruses…Resveratrol has shown strong activity against HSV1 and HSV2 in a dose-dependent manner. It appears to disrupt a critical early event in the viral reproduction cycle. Resveratrol was found to inhibit herpes simplex virus types 1 and 2 replication by the direct inactivation of HSV. Resveratrol was most effective when added within 1 hour of cell infection and was not found to be effective if added 9 hours after infection. Resveratrol was also found to delay the cell cycle reproduction and inhibit the reactivation of the virus. In another study, researchers tested a 19% resveratrol cream on skin and vaginal herpes lesions in mice and compared the results with topical acyclovir. The results were the same for both substances.
More Health Benefits of Resveratrol…Astonishingly, there have now been more than 4000 studies on the benefits of resveratrol to date proving that it helps protect the entire body. Here’s more of the powerful health benefits of resveratrol that you might want to consider…
• Resveratrol is Anti-Aging
• Resveratrol Combats Obesity
• Resveratrol Helps With Glucose Balance
• Resveratrol Helps Strengthen Bones
• Resveratrol Helps With Liver Health
• Resveratrol Protects Against Radiation
• Resveratrol Helps With Muscle Growth
• Resveratrol Increases Sex Hormones
• Resveratrol Prevents Hearing Loss
• Resveratrol is an Excellent Acne Treatment
• Resveratrol Helps Fight Infections (anti-viral, anti-fungal & anti-bacterial)
• Resveratrol Enhances Vitamin D Absorption
• Resveratrol Helps Treat Depression
• Resveratrol Increases Longevity (Already Mentioned)
Resveratrol Precautions…Since resveratrol is known to inhibit platelet aggregation and blood clot formation, people with bleeding disorders or anyone taking anti-coagulant medication should consult their physician first before taking resveratrol supplements. The potential interaction of resveratrol with these conditions is unknown at this stage.
Resveratrol Dosage…An obvious question is, "what dosage of resveratrol is necessary to gain the health benefits?" Some of the research with mice was done with a dosage of 22.4 mg’s per kg of body weight. That’s the equivalent of 1629 mg for a 160 pound adult human. Another study found similar results with an equivalent dose of 124 mg a day for a 160 pound adult. Other sources claim positive results with doses of 20 mg’s per day for humans. Translating dosages from animals to humans is an art at best and definitive dose ranging studies are still lacking. However, the best rule of thumb is to follow the directions listed on the container by the manufacturer. Do this and you can’t go wrong. Here’s some of the best resveratrol supplements currently on the market if you’re interested… Pure Organic Resveratrol Supplements
So what about getting your resveratrol from natural sources like wine? It takes approximately 10 glasses of red wine to equal the resveratrol contained in one 20 mg capsule. The negative effect of wine is that alcohol is of course detrimental to our health when consumed in excess. However, I see no problem with taking a good quality resveratrol supplement every day combined with a glass or two of Cabernet Sauvignon or Shiraz.
You still have to live!
In addition, if you are going to drink red wine, make sure the grapes are organically grown. The wide spread use of pesticides and fungicides in vineyards has unfortunately led to a drastic reduction in the resveratrol content of wine. Remember what I said earlier. Resveratrol is produced in the grapes as a defense against damage and fungus attack. With no bugs and fungus, the grapes don't need to make resveratrol. So, if you’re looking for wine or grapes or growing your own, go organic and go for humid conditions that promote fungus. It’s possible that grape varieties which are naturally fungus resistant may also be higher in resveratrol, so these are okay to consume as well.
And remember, preservative free wine only!
This Just In…
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